Alcohol dependence is a public health problem affecting about 4% of the United States population. Alcohol causes serious medical disorders such as hepatic cirrhosis, immune system disorders, brain damage, fetal alcohol syndrome, automobile accidents and fatalities, homicides and suicides. In the US, 85,000 deaths, along with disability from medical and psychiatric causes, injuries, and other effects are attributed to alcohol. The estimated annual health care cost attributed to alcohol use is $185 billion.
Counseling, behavioral therapies and self-help groups are widely used to treat alcohol dependence. However, up to 60% of subjects do not respond well to these therapies. Some experts suggest that drug therapy should be considered for all patients in whom alcohol dependence is diagnosed, who do not have medical contraindications to the drug and who are willing to take the drugs.
Of about 1,500,000 patients seeking treatment, only about 140,000 are treated with pharmacological agents because of suboptimal effect size, adverse effects, or lack of compliance. A pharmacological agent with improved properties would be of great potential benefit for patients with alcohol dependence.
Do you depend on alcohol? Does one beer turn into 6, a glass of wine into a bottle, happy hour lasts all night? If you are 21 to 65 years of age and depend on alcohol, you may be eligible for an alcohol dependency research study. Qualified candidates may receive medical evaluations, investigational medication at no cost and financial compensation for time and travel.